The Electrostatic Field Around the SOD Enzyme


This image illustrates the electrostatic field (yellow) around an active site (red) of the enzyme superoxide dismutase, which controls oxygen toxicity by converting the superoxide radical to less dangerous forms. Michael Potter of Andrew McCammon's group at the University of California, San Diego, studied the influence of the electrostatic field on the reaction with superoxide using Brownian Dynamics simulations and the UHBD software package on SDSC's CRAY C90. The results were visualized with GRASP software, by A. Nicholls and B. Honig of Columbia University, and resources in SDSC's VisLab.